Inside Front Cover: Protein amyloid aggregate: Structure and function

The amyloid-beta precursor protein: integrating structure with biological function.

Proteolytic processing of the amyloid-beta precursor protein (APP) generates the Abeta amyloid peptide of Alzheimer's disease. The biological function of APP itself remains, however, unclear. In the current review, we study in detail the different subdomains of APP and try to assign functional significance to particular structures identified in the protein.

The structure of the population inside the propagating front

We investigate the long-time and long-range behavior of branching diffusion processes (starting with a single particle) in two different situations: when the branching potential has compact support and when it is constant. For compactly supported branching potentials, the qualitative behavior of the processes depends on the intensity of the branching. We analyze the super-critical case, when th...

Proceedings Front Cover 8X10

The integrated Rule Oriented Data Management System (iRODS) is a policy-driven data management system that is starting to be used by projects with large data volume requirements that require a highly available system. In this paper we describe an approach to provide a Highly Availability load-balanced iRODS System (HAIRS). We also describe the advantages and disadvantages of the approach and fu...

Outside Front Cover

LUI Front Cover